2biv

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Template:STRUCTURE 2biv

Contents

Crystal structure of the wild-type MBT domains of Human SCML2

Template:ABSTRACT PUBMED 18706910

Function

[SCML2_HUMAN] Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).

About this Structure

2biv is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Santiveri CM, Lechtenberg BC, Allen MD, Sathyamurthy A, Jaulent AM, Freund SM, Bycroft M. The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine. J Mol Biol. 2008 Oct 24;382(5):1107-12. Epub 2008 Aug 3. PMID:18706910 doi:10.1016/j.jmb.2008.07.081

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OCA

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