2kw6

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Template:STRUCTURE 2kw6

Contents

Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H

Template:ABSTRACT PUBMED 22427660

Function

[CDKA1_HUMAN] specific inhibitor of the cell-cycle kinase CDK2 (By similarity).

About this Structure

2kw6 is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, Maglaqui M, Lee HW, Prestegard JH, Montelione GT. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region. J Biol Chem. 2012 May 11;287(20):16541-9. Epub 2012 Mar 14. PMID:22427660 doi:10.1074/jbc.M112.343863

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