2kzk

From Proteopedia

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Template:STRUCTURE 2kzk

Contents 1 Solution structure of alpha-mannosidase binding domain of Atg34 2 Function 3 About this Structure 4 Reference

Solution structure of alpha-mannosidase binding domain of Atg34

Template:ABSTRACT PUBMED 20659891

Function

[ATG34_YEAST] Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole.^{[1] [2]}

About this Structure

2kzk is a 1 chain structure with sequence from Atcc 18824. Full experimental information is available from OCA.

Reference

• Watanabe Y, Noda NN, Kumeta H, Suzuki K, Ohsumi Y, Inagaki F. Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by Atg19 and Atg34. J Biol Chem. 2010 Sep 24;285(39):30026-33. Epub 2010 Jul 21. PMID:20659891 doi:http://dx.doi.org/10.1074/jbc.M110.143545

1. ↑ Suzuki K, Kondo C, Morimoto M, Ohsumi Y. Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p. J Biol Chem. 2010 Sep 24;285(39):30019-25. doi: 10.1074/jbc.M110.143511. Epub, 2010 Jul 16. PMID:20639194 doi:http://dx.doi.org/10.1074/jbc.M110.143511
2. ↑ Watanabe Y, Noda NN, Kumeta H, Suzuki K, Ohsumi Y, Inagaki F. Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by Atg19 and Atg34. J Biol Chem. 2010 Sep 24;285(39):30026-33. Epub 2010 Jul 21. PMID:20659891 doi:http://dx.doi.org/10.1074/jbc.M110.143545