2hto

Publication Abstract from PubMed

The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.

Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.