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2pin

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Image:2pin.png

Template:STRUCTURE 2pin

Thyroid receptor beta in complex with inhibitor

Template:ABSTRACT PUBMED 17823305

About this Structure

2pin is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Estebanez-Perpina E, Arnold LA, Jouravel N, Togashi M, Blethrow J, Mar E, Nguyen P, Phillips KJ, Baxter JD, Webb P, Guy RK, Fletterick RJ. Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor. Mol Endocrinol. 2007 Dec;21(12):2919-28. Epub 2007 Sep 6. PMID:17823305 doi:10.1210/me.2007-0174

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OCA

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