3c4c
From Proteopedia
B-Raf Kinase in Complex with PLX4720
Template:ABSTRACT PUBMED 18287029
About this Structure
3c4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, Nguyen H, Lam B, Liu J, Cheung I, Rice J, Suzuki Y, Luu C, Settachatgul C, Shellooe R, Cantwell J, Kim SH, Schlessinger J, Zhang KY, West BL, Powell B, Habets G, Zhang C, Ibrahim PN, Hirth P, Artis DR, Herlyn M, Bollag G. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3041-6. Epub 2008 Feb 19. PMID:18287029
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Wang, W. | Zhang, K Y.J. | Atp-binding | B-raf | Braf | Cardiomyopathy | Disease mutation | Metal-binding | Nucleotide-binding | Phorbol-ester binding | Phosphoprotein | Proto-oncogene | Raf | Serine/threonine kinase | Serine/threonine-protein kinase | Transferase | Zinc-finger
