2r2y

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Template:STRUCTURE 2r2y

Contents 1 Crystal structure of the proteasomal Rpn13 PRU-domain 2 Function 3 About this Structure 4 Reference

Crystal structure of the proteasomal Rpn13 PRU-domain

Template:ABSTRACT PUBMED 18497827

Function

[ADRM1_MOUSE] Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.^{[1] [2]}

About this Structure

2r2y is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

• Schreiner P, Chen X, Husnjak K, Randles L, Zhang N, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M. Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature. 2008 May 22;453(7194):548-52. PMID:18497827 doi:10.1038/nature06924

1. ↑ Lamerant N, Kieda C. Adhesion properties of adhesion-regulating molecule 1 protein on endothelial cells. FEBS J. 2005 Apr;272(8):1833-44. PMID:15819879 doi:10.1111/j.1742-4658.2005.04613.x
2. ↑ Schreiner P, Chen X, Husnjak K, Randles L, Zhang N, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M. Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature. 2008 May 22;453(7194):548-52. PMID:18497827 doi:10.1038/nature06924