2wjp
From Proteopedia
Contents |
CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR
Template:ABSTRACT PUBMED 20804196
Function
[MURD_ECOLI] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]
About this Structure
2wjp is a 1 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA.
See Also
Reference
- Zidar N, Tomasic T, Sink R, Rupnik V, Kovac A, Turk S, Patin D, Blanot D, Contreras Martel C, Dessen A, Muller Premru M, Zega A, Gobec S, Peterlin Masic L, Kikelj D. Discovery of Novel 5-Benzylidenerhodanine and 5-Benzylidenethiazolidine-2,4-dione Inhibitors of MurD Ligase. J Med Chem. 2010 Aug 30. PMID:20804196 doi:10.1021/jm100285g
Categories: Bacillus coli migula 1895 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase | Blanot, D. | Contreras-Martel, C. | Dessen, A. | Gobec, S. | Kikelj, D. | Kovac, A. | Muller-Premru, M. | Peterlin-Masic, L. | Rupnik, V. | Sink, R. | Tomasic, T. | Turk, S. | Zega, A. | Zidar, N. | Cell cycle | Cell division | Cell shape synthesis | Cell wall biogenesis/degradation | Ligase | Peptidoglycan synthesis