2vwi

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2vwi

Contents 1 Structure of the OSR1 kinase, a hypertension drug target 2 Function 3 About this Structure 4 Reference

Structure of the OSR1 kinase, a hypertension drug target

Function

[OXSR1_HUMAN] Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.^[1]

About this Structure

2vwi is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

1. ↑ Chen W, Yazicioglu M, Cobb MH. Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily. J Biol Chem. 2004 Mar 19;279(12):11129-36. Epub 2004 Jan 5. PMID:14707132 doi:10.1074/jbc.M313562200