3zj7

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Template:STRUCTURE 3zj7

Contents

Crystal structure of strictosidine glucosidase in complex with inhibitor-1

Function

[SG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the therapy of heart disorders.[1]

About this Structure

3zj7 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Xia L, Ruppert M, Wang M, Panjikar S, Lin H, Rajendran C, Barleben L, Stockigt J. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity. ACS Chem Biol. 2011 Oct 28. PMID:22004291 doi:10.1021/cb200267w

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