3vep

From Proteopedia

Revision as of 05:07, 10 October 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 3vep

Contents

Crystal structure of SigD4 in complex with its negative regulator RsdA

Template:ABSTRACT PUBMED 23314154

Function

[RPSD_MYCTU] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis.[1]

About this Structure

3vep is a 8 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Jaiswal RK, Prabha TS, Manjeera G, Gopal B. Mycobacterium tuberculosis RsdA provides a conformational rationale for selective regulation of sigma-factor activity by proteolysis. Nucleic Acids Res. 2013 Jan 11. PMID:23314154 doi:http://dx.doi.org/10.1093/nar/gks1468
  1. ↑ Raman S, Hazra R, Dascher CC, Husson RN. Transcription regulation by the Mycobacterium tuberculosis alternative sigma factor SigD and its role in virulence. J Bacteriol. 2004 Oct;186(19):6605-16. PMID:15375142 doi:http://dx.doi.org/10.1128/JB.186.19.6605-6616.2004

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3vep"
Personal tools