216d

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Image:216d.jpg


PDB ID 216d

Drag the structure with the mouse to rotate
, resolution 1.730Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN


Overview

Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.

About this Structure

216D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741

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