2wqz

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Template:STRUCTURE 2wqz

Contents

CRYSTAL STRUCTURE OF SYNAPTIC PROTEIN NEUROLIGIN-4 IN COMPLEX WITH NEUREXIN-BETA 1: ALTERNATIVE REFINEMENT

Template:ABSTRACT PUBMED 18093521

Function

[NRX1B_RAT] Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity).[1]

About this Structure

2wqz is a 4 chain structure with sequence from Homo sapiens and Rattus norvegicus. This structure supersedes the now removed PDB entry 2vh8. Full crystallographic information is available from OCA.

See Also

Reference

  • Fabrichny IP, Leone P, Sulzenbacher G, Comoletti D, Miller MT, Taylor P, Bourne Y, Marchot P. Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion. Neuron. 2007 Dec 20;56(6):979-91. PMID:18093521 doi:10.1016/j.neuron.2007.11.013
  1. ↑ Nguyen T, Sudhof TC. Binding properties of neuroligin 1 and neurexin 1beta reveal function as heterophilic cell adhesion molecules. J Biol Chem. 1997 Oct 10;272(41):26032-9. PMID:9325340

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