4idw

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Template:STRUCTURE 4idw

Contents

Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy

Template:ABSTRACT PUBMED 23695242

Function

[INS_BOVIN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

About this Structure

4idw is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Margiolaki I, Giannopoulou AE, Wright JP, Knight L, Norrman M, Schluckebier G, Fitch AN, Von Dreele RB. High-resolution powder X-ray data reveal the T6 hexameric form of bovine insulin. Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):978-90. doi:, 10.1107/S0907444913003867. Epub 2013 May 11. PMID:23695242 doi:10.1107/S0907444913003867

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