3kki

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Template:STRUCTURE 3kki

Contents

PLP-Dependent Acyl-CoA transferase CqsA

Template:ABSTRACT PUBMED 19838203

Function

[CQSA_VIBCH] Required for the synthesis of the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal.

About this Structure

3kki is a 2 chain structure with sequence from Vibrio cholerae. This structure supersedes the now removed PDB entry 3hqs. Full crystallographic information is available from OCA.

Reference

  • Kelly RC, Bolitho ME, Higgins DA, Lu W, Ng WL, Jeffrey PD, Rabinowitz JD, Semmelhack MF, Hughson FM, Bassler BL. The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA. Nat Chem Biol. 2009 Dec;5(12):891-5. Epub 2009 Oct 18. PMID:19838203 doi:10.1038/nchembio.237

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