4ib4
From Proteopedia
Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine
Template:ABSTRACT PUBMED 23519215
Function
[5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
About this Structure
4ib4 is a 1 chain structure. Full crystallographic information is available from OCA.
Categories: Cherezov, V. | Chu, M. | GPCR, GPCR Network. | Han, G W. | Huang, X. | Jiang, Y. | Katritch, V. | Liu, W. | McCorvy, J D. | Roth, B L. | Siu, F Y. | Stevens, R C. | Vardy, E. | Wacker, D. | Wang, C. | Xu, H E. | Electron transport | Ergotamine | Gpcr | Gpcr dock | Gpcr network | Membrane protein | Novel protein engineering | Psi-biology | Signaling protein | Structural genomic
