4in0

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Template:STRUCTURE 4in0

Contents

Crystal Structure of human splicing factor dim2/TXNL4B

Template:ABSTRACT PUBMED 23519793

Function

[TXN4B_HUMAN] Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.[1]

About this Structure

4in0 is a 2 chain structure with sequence from Streptomyces aureorectus. Full crystallographic information is available from OCA.

Reference

  • Jin T, Guo F, Wang Y, Zhang Y. High-resolution crystal structure of human Dim2/TXNL4B. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):223-7. doi:, 10.1107/S1744309113000973. Epub 2013 Feb 22. PMID:23519793 doi:10.1107/S1744309113000973
  1. Sun X, Zhang H, Wang D, Ma D, Shen Y, Shang Y. DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression. J Biol Chem. 2004 Jul 30;279(31):32839-47. Epub 2004 May 25. PMID:15161931 doi:10.1074/jbc.M402522200

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