3jyo

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Template:STRUCTURE 3jyo

Contents

Quinate dehydrogenase from Corynebacterium glutamicum in complex with NAD

Template:ABSTRACT PUBMED 23929881

Function

[AROE_CORGL] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.[1]

About this Structure

3jyo is a 1 chain structure with sequence from Corynebacterium glutamicum atcc 13032. Full crystallographic information is available from OCA.

Reference

  • Hoppner A, Schomburg D, Niefind K. Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity and discrimination. Biol Chem. 2013 Aug 8. pii:, /j/bchm.just-accepted/hsz-2013-0170/hsz-2013-0170.xml. doi:, 10.1515/hsz-2013-0170. PMID:23929881 doi:10.1515/hsz-2013-0170
  1. ↑ Schoepe J, Niefind K, Schomburg D. 1.6 angstroms structure of an NAD+-dependent quinate dehydrogenase from Corynebacterium glutamicum. Acta Crystallogr D Biol Crystallogr. 2008 Jul;D64(Pt 7):803-9. Epub 2008, Jun 18. PMID:18566515 doi:http://dx.doi.org/10.1107/S090744490801411X

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