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4i4b
From Proteopedia
Contents |
HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA
Template:ABSTRACT PUBMED 23802607
Function
[MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
About this Structure
4i4b is a 2 chain structure with sequence from Pseudomonas mevalonii. Full crystallographic information is available from OCA.
Reference
- Steussy CN, Critchelow CJ, Schmidt TJ, Min JK, Wrensford LV, Burgner JW, Rodwell VW, Stauffacher CV. A novel role for CoA during hydride transfer in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biochemistry. 2013 Jun 26. PMID:23802607 doi:10.1021/bi400335g
