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4jr2

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Revision as of 07:56, 8 May 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4jr2

Human procaspase-7/caspase-7 heterodimer bound to Ac-DEVD-CMK

Function

[CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

About this Structure

4jr2 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

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OCA

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