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3mu3

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Template:STRUCTURE 3mu3

Contents

Crystal structure of chicken MD-1 complexed with lipid IVa

Template:ABSTRACT PUBMED 20534476

Function

[LY86_CHICK] May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).

About this Structure

3mu3 is a 2 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Yoon SI, Hong M, Han GW, Wilson IA. Crystal structure of soluble MD-1 and its interaction with lipid IVa. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10990-5. Epub 2010 Jun 1. PMID:20534476

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OCA

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