This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3j0b
From Proteopedia
Contents |
cryo-EM reconstruction of West Nile virus
Template:ABSTRACT PUBMED 23602814
Function
[Q9Q6P4_WNV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS011998_004_099774]
About this Structure
3j0b is a 3 chain structure with sequence from West nile virus. Full crystallographic information is available from OCA.
Reference
- Zhang W, Kaufmann B, Chipman PR, Kuhn RJ, Rossmann MG. Membrane curvature in flaviviruses. J Struct Biol. 2013 Apr 18. pii: S1047-8477(13)00100-7. doi:, 10.1016/j.jsb.2013.04.005. PMID:23602814 doi:10.1016/j.jsb.2013.04.005
