4kat

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Template:STRUCTURE 4kat

Contents 1 Crystal structure of FDTS from T. maritima mutant (R174K) with FAD and dUMP 2 Function 3 About this Structure 4 Reference

Crystal structure of FDTS from T. maritima mutant (R174K) with FAD and dUMP

Template:ABSTRACT PUBMED 24563811

Function

[THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.

About this Structure

4kat is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

• Mathews II. Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design. J Bioterror Biodef. 2013 Apr 20;Suppl 12:004. PMID:24563811 doi:http://dx.doi.org/10.4172/2157-2526.S12-004