4bpw

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Template:STRUCTURE 4bpw

Contents

Crystal structure of human primase bound to UTP

Template:ABSTRACT PUBMED 24043831

Function

[PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

About this Structure

4bpw is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kilkenny ML, Longo MA, Perera RL, Pellegrini L. Structures of human primase reveal design of nucleotide elongation site and mode of Pol alpha tethering. Proc Natl Acad Sci U S A. 2013 Sep 16. PMID:24043831 doi:10.1073/pnas.1311185110

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OCA

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