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4jct

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Revision as of 04:25, 18 July 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4jct

Contents

ClpP2 from Listeria monocytogenes

Template:ABSTRACT PUBMED 23798410

Function

[CLPP_LISMO] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).

About this Structure

4jct is a 7 chain structure with sequence from Listeria monocytogenes egd-e. Full crystallographic information is available from OCA.

Reference

  • Zeiler E, List A, Alte F, Gersch M, Wachtel R, Poreba M, Drag M, Groll M, Sieber SA. Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11302-7. doi:, 10.1073/pnas.1219125110. Epub 2013 Jun 24. PMID:23798410 doi:10.1073/pnas.1219125110

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OCA

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