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4g9a

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Revision as of 06:31, 14 August 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4g9a

Contents

Crystal structure of calcium2+-bound wild-type CD23 lectin domain

Template:ABSTRACT PUBMED 23775083

Function

[FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

About this Structure

4g9a is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yuan D, Keeble AH, Hibbert RG, Fabiane S, Gould HJ, McDonnell JM, Beavil AJ, Sutton BJ, Dhaliwal B. Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J Biol Chem. 2013 Jul 26;288(30):21667-77. doi: 10.1074/jbc.M113.480657. Epub, 2013 Jun 17. PMID:23775083 doi:10.1074/jbc.M113.480657

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OCA

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