4btf

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Template:STRUCTURE 4btf

Contents

Structure of MLKL

Template:ABSTRACT PUBMED 24012422

Function

[MLKL_MOUSE] Required for the execution of programmed necrosis (By similarity).

About this Structure

4btf is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S, Lewis R, Lalaoui N, Metcalf D, Webb AI, Young SN, Varghese LN, Tannahill GM, Hatchell EC, Majewski IJ, Okamoto T, Dobson RC, Hilton DJ, Babon JJ, Nicola NA, Strasser A, Silke J, Alexander WS. The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism. Immunity. 2013 Sep 4. pii: S1074-7613(13)00348-8. doi:, 10.1016/j.immuni.2013.06.018. PMID:24012422 doi:10.1016/j.immuni.2013.06.018

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