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4lcg

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Revision as of 08:25, 21 August 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4lcg

Contents

Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-050 complex

Template:ABSTRACT PUBMED 23914798

Function

[LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

About this Structure

4lcg is a 1 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

  • Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Synthesis, structure and antibiotic activity of aryl-substituted LpxC inhibitors. J Med Chem. 2013 Aug 5. PMID:23914798 doi:10.1021/jm4007774

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OCA

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