4bpp

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Template:STRUCTURE 4bpp

Contents

The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A - Complex 4

Template:ABSTRACT PUBMED 23851459

Function

[I7MK25_TETTS] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).[RuleBase:RU004365] [E6PBR9_TETTH] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (By similarity).[HAMAP-Rule:MF_03015]

About this Structure

4bpp is a 35 chain structure with sequence from Tetrahymena thermophila. Full crystallographic information is available from OCA.

Reference

  • Weisser M, Voigts-Hoffmann F, Rabl J, Leibundgut M, Ban N. The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A. Nat Struct Mol Biol. 2013 Jul 14. doi: 10.1038/nsmb.2622. PMID:23851459 doi:10.1038/nsmb.2622

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