4l16

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Template:STRUCTURE 4l16

Contents

Crystal structure of FIGL-1 AAA domain in complex with ADP

Function

[FIGL1_CAEEL] Has a role in spindle assembly which acts in the progression through mitosis during embryogenesis. Required for fertility.[1]

About this Structure

4l16 is a 1 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

  1. Luke-Glaser S, Pintard L, Tyers M, Peter M. The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line. J Cell Sci. 2007 Sep 15;120(Pt 18):3179-87. PMID:17878235 doi:10.1242/jcs.015883

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