4lrz
From Proteopedia
Contents |
Crystal Structure of the E.coli DhaR(N)-DhaL complex
Template:ABSTRACT PUBMED 24440518
Function
[DHAL_ECOLI] ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL-ADP receives a phosphoryl group from DhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sensor domain of DhaR. DhaL-ATP is inactive. [DHAR_ECOLI] Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own synthesis.
About this Structure
4lrz is a 8 chain structure. Full crystallographic information is available from OCA.
Reference
- Shi R, McDonald L, Cygler M, Ekiel I. Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR. Structure. 2014 Jan 14. pii: S0969-2126(13)00471-1. doi:, 10.1016/j.str.2013.11.012. PMID:24440518 doi:http://dx.doi.org/10.1016/j.str.2013.11.012