3w3c

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Template:STRUCTURE 3w3c

Contents 1 Crystal structure of VirB core domain complexed with the cis-acting site upstream icsb promoter 2 Function 3 About this Structure 4 Reference

Crystal structure of VirB core domain complexed with the cis-acting site upstream icsb promoter

Template:ABSTRACT PUBMED 23985969

Function

[VIRB_SHIFL] Transcription activator for the invasion antigens IpaB, IpaC and IpaD. VirB is itself regulated by VirF.

About this Structure

3w3c is a 3 chain structure with sequence from Shigella flexneri 2a. Full crystallographic information is available from OCA.

Reference

• Gao X, Zou T, Mu Z, Qin B, Yang J, Waltersperger S, Wang M, Cui S, Jin Q. Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes. Nucleic Acids Res. 2013 Dec 1;41(22):10529-41. doi: 10.1093/nar/gkt748. Epub 2013, Aug 27. PMID:23985969 doi:http://dx.doi.org/10.1093/nar/gkt748