4mk2

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Template:STRUCTURE 4mk2

3-(5-hydroxy-6-oxo-1,6-dihydropyridin-3-yl)benzonitrile bound to influenza 2009 pH1N1 endonuclease

Template:ABSTRACT PUBMED 23978130

About this Structure

4mk2 is a 1 chain structure with sequence from Influenza a virus (a/lima/wrair1695p/2009(h1n1)). Full crystallographic information is available from OCA.

Reference

  • Bauman JD, Patel D, Baker SF, Vijayan RS, Xiang A, Parhi AK, Martinez-Sobrido L, Lavoie EJ, Das K, Arnold E. Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors. ACS Chem Biol. 2013 Sep 13. PMID:23978130 doi:10.1021/cb400400j

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