4lp0
From Proteopedia
Crystal structure of a topoisomerase ATP inhibitor
Template:ABSTRACT PUBMED 24098982
About this Structure
4lp0 is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Basarab GS, Manchester JI, Bist S, Boriack-Sjodin PA, Dangel B, Illingworth R, Sherer BA, Sriram S, Uria-Nickelsen M, Eakin AE. Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J Med Chem. 2013 Oct 29. PMID:24098982 doi:http://dx.doi.org/10.1021/jm401208b
Categories: Basarab, G S. | Bist, S. | Boriack-Sjodin, P A. | Dangel, B. | Eakin, A E. | Illingsworth, R. | Manchester, J I. | Sherer, B A. | Sriram, S. | Uria-Nickelsen, M. | Antimicrobial | Atp binding | Atpase domain | Isomerase-isomerase inhibitor complex | Protein-inhibitor complex | Structure-based drug design | Virtual screen
