This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4khn
From Proteopedia
Contents |
Crystal structure of the ternary complex of the D714A mutant of RB69 DNA polymerase
Template:ABSTRACT PUBMED 24116139
Function
[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
About this Structure
4khn is a 6 chain structure with sequence from Enterobacteria phage rb69. Full crystallographic information is available from OCA.
Reference
- Jacewicz A, Trzemecka A, Guja KE, Plochocka D, Yakubovskaya E, Bebenek A, Garcia-Diaz M. A Remote Palm Domain Residue of RB69 DNA Polymerase Is Critical for Enzyme Activity and Influences the Conformation of the Active Site. PLoS One. 2013 Oct 7;8(10):e76700. doi: 10.1371/journal.pone.0076700. PMID:24116139 doi:http://dx.doi.org/10.1371/journal.pone.0076700
