4boc

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Template:STRUCTURE 4boc

Contents

Structure of mitochondrial RNA polymerase elongation complex

Template:ABSTRACT PUBMED 24096365

Function

[RPOM_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.[1]

About this Structure

4boc is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Schwinghammer K, Cheung AC, Morozov YI, Agaronyan K, Temiakov D, Cramer P. Structure of human mitochondrial RNA polymerase elongation complex. Nat Struct Mol Biol. 2013 Oct 6. doi: 10.1038/nsmb.2683. PMID:24096365 doi:http://dx.doi.org/10.1038/nsmb.2683
  1. ↑ Minczuk M, He J, Duch AM, Ettema TJ, Chlebowski A, Dzionek K, Nijtmans LG, Huynen MA, Holt IJ. TEFM (c17orf42) is necessary for transcription of human mtDNA. Nucleic Acids Res. 2011 May;39(10):4284-99. doi: 10.1093/nar/gkq1224. Epub 2011, Jan 28. PMID:21278163 doi:10.1093/nar/gkq1224

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