Sandbox Reserved 792

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This Sandbox is Reserved from Oct 10, 2013, through May 20, 2014 for use in the course "CHEM 410 Biochemistry 1 and 2" taught by Hanna Tims at the Messiah College. This reservation includes Sandbox Reserved 780 through Sandbox Reserved 807.

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spinqualitylabelsall models Citrate Synthase Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Contents 1 Introduction 2 Structure 3 Solvent Interaction 4 Active Site 5 Mechanism of Action

Introduction

Structure

Citrate Synthase is a homodimer of its A chain. It's can be seen to contain many alpha helicies. of citrate synthase is comprised of mainly alpha helices.

The shows the vast majority of the protein is alpha helices (blue-gray) with a small beta sheet (orange).

The in the backbone are shown in green.

The are shown in grey. The are in pink.

Solvent Interaction

The are shown in blue, the protein in cream and the ligand in a light purple. The water interaction (with the same color designations) are similar in the .

Active Site

The are depicted in ball in stick and the rest of the protein is in ribbon diagram. The are shown in black.

Mechanism of Action