2m5k

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Template:STRUCTURE 2m5k

Contents

Atomic-resolution structure of a doublet cross-beta amyloid fibril

Template:ABSTRACT PUBMED 23513222

Function

[TTHY_RAT] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.[1]

About this Structure

2m5k is a 8 chain structure. Full experimental information is available from OCA.

Reference

  • Fitzpatrick AW, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller SA, MacPhee CE, Waudby CA, Mott HR, De Simone A, Knowles TP, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM. Atomic structure and hierarchical assembly of a cross-beta amyloid fibril. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5468-73. doi:, 10.1073/pnas.1219476110. Epub 2013 Mar 19. PMID:23513222 doi:10.1073/pnas.1219476110
  1. ↑ Schreiber G, Aldred AR, Jaworowski A, Nilsson C, Achen MG, Segal MB. Thyroxine transport from blood to brain via transthyretin synthesis in choroid plexus. Am J Physiol. 1990 Feb;258(2 Pt 2):R338-45. PMID:2309926

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