4nc3
From Proteopedia
Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase.
Function
[5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
About this Structure
4nc3 is a 1 chain structure. Full crystallographic information is available from OCA.
Categories: Barty, A. | Basu, S. | Beyerlein, K R. | Boutet, S. | Caffrey, M. | Chapman, H N. | Cherezov, V. | Fromme, P. | Fromme, R. | GPCR, GPCR Network. | Gati, C. | Grotjohann, I. | Han, G W. | James, D. | Katritch, V. | Kirian, R A. | Koglin, J E. | Kupitz, C. | Li, D. | Liu, W. | Messerschmidt, M. | Nelson, G. | Rendek, K N. | Seibert, M M. | Shah, S T.A. | Spence, J C.H. | Stevens, R C. | Wacker, D. | Wang, C. | Wang, D. | Weierstall, U. | White, T A. | Williams, G J. | Zatsepin, N A. | Electron transport | Ergotamine | Free electron laser | Gpcr | Gpcr network | Human 5ht2b receptor | Lipidic cubic phase | Membrane | Membrane protein | Novel protein engineering | Psi-biology | Serial femtosecond crystallography | Signaling protein | Structural genomic
