4c3l

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Template:STRUCTURE 4c3l

Structure of wildtype PII from S. elongatus at high resolution

Function

[GLNB_SYNE7] P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is phosphorylated, these events are reversed. In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.

About this Structure

4c3l is a 1 chain structure. Full crystallographic information is available from OCA.

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