This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4mvd
From Proteopedia
Contents |
Crystal Structure of a Mammalian Cytidylyltransferase
Template:ABSTRACT PUBMED 24275660
Function
[PCY1A_RAT] Controls phosphatidylcholine synthesis.
About this Structure
4mvd is a 8 chain structure. Full crystallographic information is available from OCA.
Reference
- Lee J, Taneva SG, Holland BW, Tieleman DP, Cornell RB. Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. J Biol Chem. 2014 Jan 17;289(3):1742-55. doi: 10.1074/jbc.M113.526970. Epub 2013 , Nov 25. PMID:24275660 doi:http://dx.doi.org/10.1074/jbc.M113.526970
Categories: Choline-phosphate cytidylyltransferase | Cornell, R B. | Lee, J. | Amphipathic helix | Cytidine 5'-diphosphocholine synthesis | Endoplasmic reticulum | Four-helix bundle | Lipid membrane binding | Lipid membrane surface | Nucleus | Phosphatidylcholine homeostasis | Rossmann fold | Transferase
