Sandbox Reserved 825
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This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543. |
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FRB Domain
mTOR is highly conserved across all eukaryotes, with 40–60% amino-acid sequence identity.
mTOR contains a number of distinct functional domains including up to The FRB domain of mTOR (or 2NPU) which is responsible for the binding of the inhibitory cyclic macrolide Rapamycin