4cmw

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Template:STRUCTURE 4cmw

Contents

Crystal structure of Rv3378c

Template:ABSTRACT PUBMED 24516143

Function

[TUBOL_MYCTU] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro.

About this Structure

4cmw is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Layre E, Lee HJ, Young DC, Jezek Martinot A, Buter J, Minnaard AJ, Annand JW, Fortune SM, Snider BB, Matsunaga I, Rubin EJ, Alber T, Moody DB. Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proc Natl Acad Sci U S A. 2014 Feb 10. PMID:24516143 doi:http://dx.doi.org/10.1073/pnas.1315883111

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