4mb8

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Template:STRUCTURE 4mb8

Contents

Evolutionary history and metabolic insights of ancient mammalian uricases

Template:ABSTRACT PUBMED 24550457

Function

[URIC_CANFA] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

About this Structure

4mb8 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Kratzer JT, Lanaspa MA, Murphy MN, Cicerchi C, Graves CL, Tipton PA, Ortlund EA, Johnson RJ, Gaucher EA. Evolutionary history and metabolic insights of ancient mammalian uricases. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3763-8. doi:, 10.1073/pnas.1320393111. Epub 2014 Feb 18. PMID:24550457 doi:http://dx.doi.org/10.1073/pnas.1320393111

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OCA

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