4pp8

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Template:STRUCTURE 4pp8

Contents

Crystal structure of murine NK cell ligand RAE-1 beta in complex with NKG2D

Template:ABSTRACT PUBMED 11825567

Function

[NKG2D_MOUSE] Receptor for RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1. Involved in the immune surveillance exerted by T and B lymphocytes.[1] [RAE1B_MOUSE] Acts as a ligand for NKG2D.[2]

About this Structure

4pp8 is a 4 chain structure. This structure supersedes the now removed PDB entry 1jsk. Full crystallographic information is available from OCA.

Reference

  • Li P, McDermott G, Strong RK. Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D. Immunity. 2002 Jan;16(1):77-86. PMID:11825567
  1. ↑ Carayannopoulos LN, Naidenko OV, Fremont DH, Yokoyama WM. Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D. J Immunol. 2002 Oct 15;169(8):4079-83. PMID:12370332
  2. ↑ Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity. 2000 Jun;12(6):721-7. PMID:10894171

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