4lcj

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Template:STRUCTURE 4lcj

Contents

CtBP2 in complex with substrate MTOB

Template:ABSTRACT PUBMED 24657618

Function

[CTBP2_HUMAN] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.

About this Structure

4lcj is a 8 chain structure. Full crystallographic information is available from OCA.

Reference

  • Hilbert BJ, Grossman SR, Schiffer CA, Royer WE Jr. Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. FEBS Lett. 2014 Mar 19. pii: S0014-5793(14)00231-2. doi:, 10.1016/j.febslet.2014.03.026. PMID:24657618 doi:http://dx.doi.org/10.1016/j.febslet.2014.03.026

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OCA

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