User:Daud Akhtar/Sandbox 1

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This is a default text for your page Daud Akhtar/Sandbox 1 Glucose 6 Phophate Dehydrogenease is an enzyme that plays a key role in the pentose phosphate pathway ^[1]

Glucose-6-Phosphate Dehydrogenase Deficiency

Classification

The World Health Organization classifies G6PD genetic variants into five classes, the first three of which are deficiency states.^[2]

1. Severe deficiency (<10% activity) with chronic (nonspherocytic) hemolytic anemia
2. Severe deficiency (<10% activity), with intermittent hemolysis
3. Mild deficiency (10-60% activity), hemolysis with stressors only
4. Non-deficient variant, no clinical sequelae
5. Increased enzyme activity, no clinical sequelae