Structural highlights
4ac0 is a 1 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , |
| Related: | 2xgc, 3zqg, 3zqf, 2xge, 2xgd, 3zqi, 3zqh, 4abz |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[TETR2_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
See Also