Human P-glycoprotein (ABCB1, P-gp) is a membrane protein present primarily in sanctuary sites, such as the blood-brain barrier, blood-testes barrier, placenta, and gut. The exact mechanism and quantity of molecules bound to P-gp during one transport cycle has not been confirmed experimentally, however recent advances in structural information have begun to reveal a more detailed image of subtrate binding to P-gp [1]
Function
Disease
Relevance
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
