Structure of human tissue factor (dark green) complex with coagulation factor VIIa heavy chain (red) and light chain (aqua) and Ca+2 ion (green) (PDB code 2aer).
Tissue factor (TF) is a high-affinity receptor for the blood coagulation factor VII. The TF/factor VII complex is responsible for the initiation of the coagulation protease cascade.
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Structural highlights
3D structures of tissue factor
Updated on 15-December-2014
References
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